AKI case: Mrs. Davies's labs and nursing priorities
For a 70-year-old woman admitted with acute kidney injury after four days of breathlessness and weakness, with heart failure, type 2 diabetes and hypertension and admitted medication non-adherence, interpret her laboratory results, identify the most likely cause, propose further tests, and give priority nursing diagnoses and interventions for fluid retention.
Editorial process
Last reviewed · August 14, 2026
Prerenal, intrinsic or postrenal — and what decides it
Frame the interpretation around the standard classification, because every question in the case depends on it. Acute kidney injury is prerenal, intrinsic or postrenal, and Mrs. Davies's history contains candidates for more than one. Decompensated heart failure reduces renal perfusion and produces prerenal injury; long-standing diabetes and hypertension predispose to intrinsic disease; and her admission that she has not been taking her medications regularly cuts both ways, since stopping a diuretic worsens congestion while stopping antihypertensives leaves pressure uncontrolled. So the laboratory interpretation is not a matter of reading values in isolation but of asking which pattern they form. The urea-to-creatinine relationship, the urine sodium and fractional excretion of sodium, urine specific gravity and the urinalysis sediment are the discriminators, and the answer should say what each would show under each mechanism rather than only reporting the numbers given. Saying what a value would look like under the mechanism you are rejecting is what turns a list of results into an interpretation.
The clinical picture points strongly toward volume overload rather than depletion: she reports puffiness in her legs and hands, she has not been urinating much, and she has four days of increasing breathlessness on a background of heart failure. That combination — oedema, reduced urine output and dyspnoea — is what makes fluid retention the focus of the final two questions, and it also constrains the interventions. Priority nursing diagnoses should be written properly, with the problem, the related factor and the evidence from this patient, and excess fluid volume related to compromised regulatory mechanisms is the obvious first. The interventions then follow directly: daily weights at the same time on the same scale as the most sensitive measure, strict intake and output, fluid and sodium restriction as ordered, respiratory assessment, positioning, skin care over oedematous areas, and monitoring electrolytes. Say why daily weight beats intake and output charts, because that reasoning is what is being tested.
Likely learning objectives
Inferred from the brief — check these against your own rubric.
- 01Classify acute kidney injury as prerenal, intrinsic or postrenal.
- 02Interpret renal laboratory results as a pattern rather than as isolated values.
- 03Identify which further tests would discriminate between candidate mechanisms.
- 04Write priority nursing diagnoses with related factors and supporting evidence.
- 05Select and justify nursing interventions for excess fluid volume.
Read the full question
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Turn the brief into deliverables
- 01An interpretation of Mrs. Davies's laboratory results and their significance.
- 02The most likely cause of her acute kidney injury.
- 03Additional tests that could determine the cause.
- 04Priority nursing diagnoses addressing fluid retention.
- 05Priority nursing interventions for those diagnoses.
Labs, cause, further tests, diagnoses, interventions
Interpreting the laboratory results
The values read together as a pattern, with their significance stated.
Classifying the injury
Prerenal, intrinsic and postrenal weighed against her history and findings.
The most likely cause
The mechanism her presentation best supports, and why.
Further tests
Tests chosen because they discriminate between the remaining candidates.
Priority nursing diagnoses
Fluid-related diagnoses written with related factors and this patient's evidence.
Priority interventions
Daily weights, intake and output, restrictions, monitoring and skin care, each justified.
AKI classification and fluid volume management
Recommended databases
- StatPearls via NCBI Bookshelf
- MedlinePlus
- PubMed
- KDIGO acute kidney injury guidance
- Course pathophysiology text
Search sequence
- 1.Read the prerenal, intrinsic and postrenal classification and its discriminators.
- 2.Note what urea, creatinine, urine sodium and specific gravity show under each.
- 3.Read how heart failure produces renal hypoperfusion.
- 4.Read on fluid volume excess assessment, especially daily weight.
- 5.Collect nursing interventions for fluid overload with their rationales.
Reference shortlist
These are authoritative starting points, not a ready-made bibliography. A qualified reviewer must confirm that each source fits the assignment and supports the claim beside which it is cited.
Nothing here is cleared for citation until you have read it.
- 01
Acute Kidney Injury
StatPearls, NCBI Bookshelf · 2024
The classification, laboratory discriminators and causes that the first three questions turn on.
- 02
Heart Failure
MedlinePlus, National Library of Medicine · 2024
The comorbidity driving both her breathlessness and the prerenal mechanism.
- 03
Diabetic Nephropathy
StatPearls, NCBI Bookshelf · 2024
The intrinsic pathway her long-standing diabetes makes plausible.
- 04
Fluid and Electrolyte Balance
MedlinePlus, National Library of Medicine · 2024
The physiology behind the fluid-retention diagnoses and the monitoring interventions.
Review before submission
Common mistakes
- Reporting laboratory values without saying what pattern they form.
- Naming one cause without weighing the others her history supports.
- Overlooking medication non-adherence as a contributing factor in both directions.
- Writing nursing diagnoses as medical diagnoses or as bare problem labels.
- Listing interventions with no rationale attached to any of them.
- Missing daily weight as the most sensitive measure of fluid status.
Submission checklist
- The AKI is classified and the classification is justified.
- Laboratory results are interpreted together rather than singly.
- Proposed tests would actually discriminate between mechanisms.
- Nursing diagnoses include problem, related factor and evidence.
- Interventions are prioritised and each carries a rationale.
- All five posed questions are answered.
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Argumentation and thesis development
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