Every order is original, expert-done, and screened for AI — full report on request.See how it works

Assignment questions
NursingCase studyPsychopharmacology

Adult and geriatric antidepressant therapy decision tree

The three-decision antidepressant prescribing case for an elderly Hispanic man with major depressive disorder: what to write under each of the four sub-questions, how to state an expectation you can be wrong about, and where the pharmacokinetic and ethical requirements sit.

Updated

Editorial process

Last reviewed · August 7, 2026

01

Twelve answers, and a structure that should be visible

This is a decision tree, not an essay, and the structure the brief prescribes should appear literally as your headings. Three decision points, each with the same four sub-questions — which decision you selected, why, what you hoped to achieve, and how the result differed from what you expected — plus a section on ethical considerations. That is twelve answers and a closing section, and a flowing narrative buries them all. Markers working through a rubric are checking for twelve specific items; if they have to hunt for the third sub-answer of Decision #2 inside a paragraph about serotonergic mechanisms, you lose marks you actually earned. Head each decision, head each sub-question, and let the document look like the instruction sheet. Reproducing the instruction sheet as headings is not lazy formatting; it is the fastest way to guarantee that nothing on the rubric goes unanswered.

The fourth sub-question is the one that separates papers and it is structurally easy to fail. *Explain any difference between what you expected to achieve and the results of the decision* only works if you committed to an expectation first, in the sub-answer above it, and stated it specifically enough to be wrong — a percentage reduction, a timeframe, a side effect profile you were willing to accept. Writing 'I expected improvement' and then reporting improvement answers nothing. The case is also built so that something goes partly sideways at each stage; that is why there are three decisions rather than one. If your answer to this sub-question is that there was no difference, you have either misread the outcome or skipped past the detail the case planted. A rating scale gives you the units for that expectation, so use the number rather than describing the direction of travel.

A related trap is retrospective justification. You see the outcome of each decision before writing about it, which makes it very tempting to justify the choice using knowledge you did not have when making it. That is circular, and it is visible: a rationale that references the result reads as though the decision could not have gone otherwise. Write each *why did you select this* answer using only what was known at that point — the presentation, the rating scale score, the side effect profile, the guideline — and keep the outcome strictly inside the fourth sub-answer. The assignment is assessing prescribing reasoning under uncertainty, and reasoning that has already seen the answer demonstrates nothing. Write the four sub-answers in the order given rather than the order they occurred to you, since that order is what keeps the outcome out of the rationale.

*Be sure to consider factors that might impact the client's pharmacokinetic and pharmacodynamic processes* is the graded clinical content, and it is where a generic depression paper gets exposed. For an older adult: reduced hepatic metabolism and renal clearance, lower serum albumin altering the free fraction of highly protein-bound drugs, greater sensitivity to orthostatic hypotension, hyponatraemia and falls, and polypharmacy raising the odds of a cytochrome interaction. Ancestry belongs here too, but as a pharmacogenomic variable rather than a cultural one — the frequency of reduced-function CYP2D6 and CYP2C19 alleles differs between populations and affects exposure to several antidepressants. Keeping that separate from the cultural discussion is the distinction the strongest submissions make. None of this is generic geriatric prescribing either: each factor has to be attached to the specific agent you selected, or it reads as background rather than reasoning.

The ethics section is a requirement rather than a flourish, and this case supplies its own material. Informed consent for an augmentation strategy or an off-label use is one strand. Discussing sexual side effects candidly is another, and it matters here because a patient who stops a working medication without saying why is a predictable outcome of a conversation nobody had. Then autonomy against beneficence when a client wants to discontinue something that is helping, language and interpreter use where the clinician and client do not share a first language, and confidentiality when family are involved in an older adult's care. Support the rationale with at least three academic resources, and note that the course text does not count toward that minimum. Ethics also belongs in the decision rationales themselves where it applies, not only in the closing section the brief asks for separately.

What the brief requires

The submission that loses marks

What earns them

Three decision points

A continuous narrative

Headed sections mirroring the instructions

Why you selected the decision

Justified using the outcome

Only what was known at that point

What you hoped to achieve

General improvement

A magnitude and a timeframe

Difference from expectation

There was no difference

The specific way the case diverged

Pharmacokinetic and pharmacodynamic factors

Generic depression pharmacology

Age-related clearance, protein binding, CYP variation

Ethical considerations

A closing sentence

Consent, side effect disclosure, autonomy, language

Three academic resources

The course text counted

Three sources besides the text

Likely learning objectives

Inferred from the brief — check these against your own rubric.

  • 01
    Justify a prescribing decision using only information available at the time.
  • 02
    State an expected outcome specifically enough to be falsified.
  • 03
    Apply age-related pharmacokinetic change to antidepressant selection.
  • 04
    Separate pharmacogenomic from cultural considerations in the same case.
Assignment instructionsQuoted verbatim

Read the full question

Review every instruction before using the planning guidance that follows.

To prepare for this Assignment: • Review this week’s Learning Resources. Consider how to assess and treat adult and geriatric clients requiring antidepressant therapy. The Assignment Examine Case Study: An Elderly Hispanic Man with Major Depressive Disorder. You will be asked to make three decisions concerning the medication to prescribe to this client. Be sure to consider factors that might impact the client’s pharmacokinetic and pharmacodynamic processes. • At each decision point stop to complete the following : • Decision #1 o Which decision did you select? o Why did you select this decision? Support your response with evidence and references to the Learning Resources. o What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources. o Explain any difference between what you expected to achieve with Decision #1 and the results of the decision. Why were they different? • Decision #2 o Why did you select this decision? Support your response with evidence and references to the Learning Resources. o What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources. o Explain any difference between what you expected to achieve with Decision # 2 and the results of the decision. Why were they different? • Decision #3 o Why did you select this decision? Support your response with evidence and references to the Learning Resources. o What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources. o Explain any difference between what you expected to achieve with Decision #3 and the results of the decision. Why were they different? © 2015 Laureate Education, Inc. Page 13 of 45 Week 3 Adult and Geriatric Antidepressant Therapy • Also include how ethical considerations might impact your treatment plan and communication with clients. Note: Support your rationale with a minimum of three academic resources. While you may use the course text to support your rationale, it will not count toward the resource requirement
02

What the assignment has to contain

  1. 01
    Three decision points, each identifying the decision selected.
  2. 02
    A rationale for each decision, supported with evidence and references.
  3. 03
    What you hoped to achieve with each decision.
  4. 04
    An explanation of any difference between expectation and result, at each point.
  5. 05
    How ethical considerations might impact the treatment plan and communication.
  6. 06
    A minimum of three academic resources, excluding the course text.
03

Working the three decisions in order

01

Set out the client and the baseline

Presentation, rating scale score, comorbidity and current medications, briefly.

02

Decision one, prospectively justified

Selection, rationale from guideline and side effect profile, a specific expected response and timeframe.

03

Report the divergence honestly

What actually happened, and why it differed from what you predicted.

04

Decisions two and three

Switch, augment or continue, each with its own four answers and its own evidence.

05

Work the pharmacokinetics into the rationales

Clearance, protein binding, interaction risk and metaboliser status, attached to the drug actually chosen.

06

Close on ethics and communication

Consent for augmentation, candid side effect discussion, autonomy, interpreter use, family involvement.

04

Sourcing the specific drug, not the class

Recommended databases

  • PubMed and NCBI Bookshelf
  • CINAHL
  • Clinical Pharmacogenetics Implementation Consortium guidelines
  • Your course Learning Resources, which the rationales must reference

Search sequence

  1. 1.
    Look up the specific agent you selected rather than the class, since the rationale has to defend that drug.
  2. 2.
    Find the age-related prescribing cautions for it — hyponatraemia, falls, QT interval, anticholinergic burden.
  3. 3.
    Check the pharmacogenomic guidance for the metabolic pathway that agent uses before writing the ancestry paragraph.
  4. 4.
    Confirm three sources besides the course text, because the text is explicitly excluded from the minimum.
05

Agent-level pharmacology and metaboliser guidance

These are authoritative starting points, not a ready-made bibliography. A qualified reviewer must confirm that each source fits the assignment and supports the claim beside which it is cited.

Nothing here is cleared for citation until you have read it.

  1. 01

    Sertraline

    StatPearls, NCBI Bookshelf, National Library of Medicine · 2023

    Indications, mechanism, adverse effects including sexual dysfunction, and monitoring. Useful when a serotonin reuptake inhibitor is the first decision, because the rationale needs drug-specific detail rather than a description of the class.

  2. 02

    Antidepressants

    StatPearls, NCBI Bookshelf, National Library of Medicine · 2023

    The classes side by side, with the differences that drive a switch or an augmentation decision. This is the source for decisions two and three, where the question is not whether to treat but what to change and why.

  3. 03

    Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants

    Clinical Pharmacology & Therapeutics, via PubMed · 2023

    Prescribing recommendations by metaboliser phenotype for specific antidepressants. This is what turns the ancestry element of the case into a pharmacokinetic argument with a guideline behind it, rather than an assertion that ethnicity matters.

06

Before the assignment is submitted

Common mistakes

  • Writing the case as continuous prose instead of the prescribed structure.
  • Justifying a decision with the outcome you already saw.
  • Stating an expectation too vague to be wrong.
  • Answering that there was no difference between expectation and result.
  • Discussing depression pharmacology generally rather than this client's.
  • Treating ethnicity as cultural only, ignoring the metabolic variation.
  • Leaving ethics to a single closing sentence.
  • Counting the course text toward the three required resources.

Submission checklist

  • All three decision points appear under their own headings.
  • Each of the four sub-questions is answered separately at every point.
  • No rationale references an outcome that had not yet occurred.
  • Each expectation includes a magnitude or a timeframe.
  • Age-related pharmacokinetic changes are applied to the specific drug chosen.
  • Cytochrome variation and polypharmacy are addressed.
  • The ethics section covers consent, disclosure and communication.
  • Three academic resources besides the course text are cited.

Use this guide to plan and review your own work. Follow your institution's rules and read our academic-integrity policy.

Written by

Aaron Bishop

MA, Education

assignment interpretation and research-methods coaching across disciplines

Aaron leads the EssayCrackers editorial desk. He works on how assignment briefs are read — what a rubric is actually asking for, and where students most often answer a different question than the one set.

Reviewed by

Dr. Nathan Cole

PhD, Rhetoric & Composition

Argumentation and thesis development

Nathan teaches first-year composition and directs a university writing center. He reviews EssayCrackers guides for argumentative soundness and citation accuracy.

Want feedback on your plan before you draft?

Get help interpreting the brief, checking your evidence strategy, and strengthening your outline while keeping the work your own.

Get assignment guidance
Start your order