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Assignment questions
NursingCase studyDermatology

NURS 6531 integumentary case studies: planning guide

Each case contains one finding that settles the diagnosis and at least one that points confidently the wrong way — including a size criterion that would rule out the correct answer in case two.

Updated

Editorial process

Last reviewed · August 6, 2026

01

One finding settles it; another points the wrong way

Each of the three cases is built around a specific wrong answer that the presentation invites, and the assignment's middle question is asking you to name the feature that rules it out.

The Forum asks for a primary diagnosis, three differentials, the role the history and physical examination played, and treatment options. That third element is where most posts go thin, because it is easy to write that the history and examination were important and hard to say which single finding moved the diagnosis. Every one of these cases contains one discriminating feature and at least one feature pointing confidently the wrong way. Identify both, and the post writes itself; identify neither, and you produce a description of the patient followed by a diagnosis that appears from nowhere. The stems are written this way deliberately, which is worth knowing before you read them: each detail is either load-bearing or bait, and very little is filler. Read each stem twice before deciding, once for the clinical picture and once asking what each specific detail was put there to do.

In the first case the distribution is the diagnosis. A pruritic eruption with tiny vesicles and scaling in the finger web spaces, on the wrists, around the belt line and on the feet and ankles, sparing the face and trunk, is a pattern rather than a rash — and the pattern is what separates it from the eczematous and contact differentials that would otherwise fit a scaly itchy rash. The recent hotel stays are the feature pointing the wrong way, because they invite bed bugs, and bed bug bites do not concentrate in web spaces. Itch that is worse at night, and the question of whether anyone in the household is also itching, are the two history items that most efficiently confirm the pattern. Both are questions the stem does not answer, which means naming them demonstrates you know what you would still need to ask rather than only what you were given.

The second case is the one where a criterion most students trust will actively mislead them. The lesion has an irregular border, uneven dark colour, a scaly surface and a two-year history of changing colour, in a fair-skinned outdoor worker with heavy adolescent ultraviolet exposure — and it is 0.2 cm across. Against the ABCDE mnemonic, the D for diameter greater than 6 mm is the single criterion this lesion fails, and it is the criterion most likely to be treated as decisive. It should not be. Depending on the series, somewhere between 2% and 38% of diagnosed melanomas measure under 6 mm, with around 30% found below that threshold. A criterion that would miss roughly a third of cases cannot carry a decision on its own, and treating it as though it can is how a small melanoma gets watched instead of biopsied.

Case

The discriminating feature

The feature that misleads

1 Pruritic rash

Distribution: web spaces, wrists, belt line, sparing face and trunk

Recent hotel stays, which suggest bed bugs

2 Changing lesion

Two years of evolution, plus border and colour irregularity

Diameter of 0.2 cm, well under the 6 mm criterion

3 Facial lesions

Unilateral distribution with pain and tingling preceding appearance

A documented eczema history and a plausible occupational exposure

The E for evolving is doing the work here, and there is evidence for treating it as the strongest of the five rather than the last one listed. In roughly 70% of early-detected melanomas the patient noticed the lesion changing before seeking care, the most commonly identified feature is a change in size, and focusing on change rather than on irregularity is more likely to identify melanoma early. So the defensible reading of this case is that four of five criteria are met, the fifth is the weakest, and the patient's own two-year observation of change is the strongest single piece of evidence in the stem. Saying that explicitly is a stronger post than reciting the mnemonic, because it shows you can weight criteria against one another rather than only check them off, which is the actual skill the case is testing.

The third case contains the sharpest clinical trap in the set, and it is not a diagnostic one. The patient has unilateral lesions on the right side of the face and neck, with itching plus tingling and pain, and she has arrived with a self-diagnosis and a specific request: a refill of triamcinolone 0.1%. Her eczema history is real and her occupational-exposure theory is plausible, which is exactly what makes it a trap. Unilateral distribution that respects a boundary, together with pain and tingling that accompany or precede the lesions, is not how eczema behaves, and prescribing the topical steroid she has asked for treats the wrong disease. The clinical lesson here is uncomfortable and worth stating: the patient has given you a coherent story, and the coherence is what makes it persuasive rather than what makes it correct.

Two things follow from that and both belong in the treatment section. If this is herpes zoster in a facial distribution, the ophthalmic division of the trigeminal nerve is a live concern — herpes zoster ophthalmicus accounts for something like 10% to 20% of zoster cases, and antiviral therapy is most effective at preventing ocular involvement when started within 72 hours of rash onset, with no data supporting efficacy after that window. That makes this a time-critical presentation rather than a routine one. Topical corticosteroids in this setting are not a substitute for antiviral therapy and should never be given without it, which is precisely what a refill would amount to. Writing that sentence in your treatment section -- naming what you would decline to prescribe and why -- is worth more than any number of correct choices, because it shows the request was recognised and refused rather than simply not considered.

For the treatment section generally, the assignment says potential treatment options based on your diagnosis, which is an invitation to specify rather than to name a drug class. Say what, at what strength, for how long, what the patient is told about contacts or household members where relevant, what follow-up interval, and what would make you escalate. For the pigmented lesion the answer is not a treatment at all but a procedure and a referral, and recognising that a biopsy decision is the intervention is itself part of the answer. For the pruritic rash the plan does not stop at the patient either, since simultaneous treatment of household members and close contacts is what prevents the reinfestation that otherwise brings them back in three weeks.

Three differentials are required alongside the primary, and they should be diagnoses that were genuinely in contention for this patient rather than a list of everything that causes a rash. For each, name the feature in the stem that argues against it. That is the same discipline the history-and-physical question is asking about, applied one differential at a time, and it converts a list into reasoning.

Name the discriminating feature, name the feature that misleads, and let the treatment section show you know which of these three cases cannot wait.

Likely learning objectives

Inferred from the brief — check these against your own rubric.

  • 01
    Identify the single examination or history finding that discriminates between competing dermatological diagnoses.
  • 02
    Recognise when a diagnostic mnemonic's weakest criterion would exclude a correct diagnosis.
  • 03
    Distinguish a plausible patient self-diagnosis from the presentation's actual pattern.
  • 04
    Recognise a time-critical dermatological presentation and act within its treatment window.
  • 05
    Specify treatment concretely rather than naming a drug class.
Assignment instructionsQuoted verbatim

Read the full question

Review every instruction before using the planning guidance that follows.

Diagnosing Integumentary Disorders When entering examination rooms, advanced practice nurses often immediately begin assessing patients by looking for external abnormalities such as skin irritations or cloudy eyes. By making these simple observations, they can determine how to proceed with their patient evaluations. During the patient evaluation, advanced practice nurses will use initial observations to guide them in acquiring the necessary medical history, performing additional assessments, and ordering the appropriate diagnostics. The information obtained during this evaluation process will help in the development of a differential diagnosis. Once a diagnosis is made, the advanced practice nurse can consider potential treatment options and work with the patient to develop a plan of care. For this Forum, consider the following three case studies of patients presenting with integumentary disorders. Case Study 1 A 46-year-old male presents to the office complaining of a pruritic skin rash that has been present for a few weeks. He initially noted the rash on his feet, but it then spread to between the fingers, his wrist, and waist. He notes that it does not seem to be on his face or trunk. He recently came home from a trip to Florida where he had stayed in multiple hotels. He takes occasional ibuprofen for knee pain, but denies taking other medications or having other health problems. He has no known drug allergies. The physical examination reveals a male with several tiny vesicles and scales in between the fingers, on the feet and ankles, around the patient’s wrist and around the belt line. Picture of a hand that is covered in a pruritic skin rash between the fingers, which covers the wrist. The rash does not uniformly cover the hand and is scaly in some areas. Case Study 2 K.B., a 52 year old Irish American patient who present today complaining of “a mole” on the skin that is changing colors. He said he has had this ‘mole’ for almost two years. K.B. is a construction worker currently residing in Hawaii. As a teen he worked outside and visited the tanning bed several times a month. He is a worried that this “mole” doesn’t look like the others on his body. On your examination, you note, the lesion as round, dark colored in appearance, and scaly. You also note the mole has an irregular border and about 0.2cm in size. Depicted on the skin are four moles. In the center is a large mole that is dark colored in appearance, with an uneven colored tone, appears scaly, and has an irregular border. The other three moles depicted appear normal in appearance. Case Study 3 J.V. 50 year old patient with history of eczema is here today complaining of lesions on the right side of her face and neck. She thinks it is a flare up of her eczema and is asking for a refill of her ointment, TAC 0.1%. She complains of some ‘itching’ and a bit of ‘tingling and pain’ to the lesions. She’s a pharmaceutical worker and thinks that the ‘pain’ maybe due to contaminate exposure. Denies any other associating symptoms. Below is a photo of the lesions. Patient presents with lesions on the right side of her face and neck. The lesions are red in appearance and vary in size. They appear scaly and do not uniformly cover the entire region of her face or neck. To prepare: Review Part 5 of the Buttaro et al. text and the case studies provided You will either select or be assigned one of the three case studies provided. Reflect on the provided patient information including history and physical exams. Think about a differential diagnosis. Consider the role the patient history and physical exam played in your diagnosis. Reflect on potential treatment options based on your diagnosis. Note: For this Forum, you are required to complete your initial post before you will be able to view and respond to your colleagues’ postings. Begin by clicking on the “Post to Forum Question” link and then select “Create Thread” to complete your initial post. Remember, once you click on Submit, you cannot delete or edit your own posts, and you cannot post anonymously. Please check your post carefully before clicking on Submit! By Day 3 Post an explanation of the primary diagnosis, as well as 3 differential diagnoses, for the patient in the case study that you selected or were assigned. Describe the role the patient history and physical exam played in the diagnosis. Then, suggest potential treatment options based on your patient diagnosis.
02

Turn the brief into deliverables

  1. 01
    An explanation of the primary diagnosis for the selected or assigned case.
  2. 02
    Three differential diagnoses for that same patient.
  3. 03
    A description of the role the patient history and physical examination played in reaching the diagnosis.
  4. 04
    Potential treatment options based on the diagnosis.
  5. 05
    An initial post submitted by Day 3, before viewing colleagues' postings.
03

Structuring the Day 3 post

01

The primary diagnosis

State it, then give the pattern that supports it.

02

The discriminating feature

The single finding that moved the diagnosis.

03

Three differentials

Each with the stem feature that argues against it.

04

What the stem gets you to think

The misleading feature, named and set aside with a reason.

05

Treatment, specified

Agent, strength, duration, follow-up, escalation criteria, contacts.

04

Look up the limits of the mnemonic, not just the mnemonic

Recommended databases

  • Buttaro et al. Primary Care text, Part 5
  • AAFP American Family Physician
  • CDC condition pages
  • PubMed

Search sequence

  1. 1.
    Read Part 5 of the assigned text for the case's condition before searching more widely.
  2. 2.
    For any mnemonic you plan to use, find a source discussing its limitations rather than only its content.
  3. 3.
    Check whether the condition has a time-limited treatment window, and cite the number of hours or days.
  4. 4.
    Look up whether treatment extends to household members or contacts.
  5. 5.
    Confirm dosing and duration from a clinical source rather than from a textbook summary.
05

Reference shortlist

These are authoritative starting points, not a ready-made bibliography. A qualified reviewer must confirm that each source fits the assignment and supports the claim beside which it is cited.

Nothing here is cleared for citation until you have read it.

  1. 01

    Clinical Diagnosis of Melanoma | AFP

    American Family Physician, American Academy of Family Physicians · 2008

    The clinical framework for the second case, and the reason its 0.2 cm diameter is not reassuring. Covers the ABCDE criteria and their application in primary care, which is the context in which the D criterion is most likely to be treated as decisive. Used alongside the evidence that a substantial minority of melanomas are under 6 mm at diagnosis -- between 2% and 38% across series, with around 30% found below that threshold -- to argue that a lesion failing only the diameter criterion is not thereby excluded.

  2. 02

    Evaluation and Management of Herpes Zoster Ophthalmicus | AFP

    American Family Physician, American Academy of Family Physicians · 2002

    The urgency argument for the third case. Herpes zoster ophthalmicus arises from reactivation in the ophthalmic division of the trigeminal nerve and accounts for roughly 10% to 20% of zoster cases; antiviral therapy is most effective at preventing ocular involvement when started within 72 hours of rash onset, and there are no data supporting efficacy begun after that window. This is what makes a unilateral facial eruption a time-critical presentation rather than a routine dermatological one, and what makes refilling a topical steroid the wrong response to the patient's request.

  3. 03

    About Scabies | Scabies | CDC

    Centers for Disease Control and Prevention · 2025

    The distribution and transmission facts behind the first case, and the source for the part of the answer that extends past the patient. Covers the characteristic sites -- finger web spaces, wrists, waist, feet and ankles -- the nocturnal intensification of itch, and the requirement to treat household members and close contacts simultaneously whether or not they are symptomatic, which is the element of the treatment plan that a diagnosis-focused post most often omits.

  4. 04

    A systematic review of the frequency of features of the seven-point checklist in proven cutaneous melanoma: The importance of change

    PubMed Central, US National Library of Medicine · 2023

    The evidence for weighting evolution above the other criteria rather than listing it last. Change in the lesion is the most commonly identified feature in proven melanoma, and focusing on change rather than on irregularity is more likely to identify melanoma early -- which supports the guide's argument that the second case's two-year history of colour change is the single strongest item in the stem, outweighing the diameter that appears to argue against the diagnosis.

06

Review before submission

Common mistakes

  • Stating that the history and physical were important without naming which finding was decisive.
  • Treating diameter under 6 mm as ruling out melanoma when it is the weakest of the five criteria.
  • Reciting the ABCDE mnemonic rather than weighting evolution above the rest.
  • Accepting the patient's own eczema self-diagnosis because the history supports it.
  • Prescribing the topical steroid the patient requested, which treats the wrong disease.
  • Missing that a facial zoster presentation is time-critical rather than routine.
  • Following the hotel-stay detail toward bed bugs when the distribution does not fit.
  • Listing three differentials that were never in contention for this specific patient.
  • Naming a drug class instead of specifying agent, strength, duration and follow-up.
  • Omitting household or contact management where the diagnosis requires it.

Submission checklist

  • One case is addressed, the one selected or assigned.
  • The primary diagnosis is stated plainly before it is justified.
  • Exactly three differentials appear, each genuinely plausible for this patient.
  • Each differential names the stem feature that argues against it.
  • The discriminating finding is identified explicitly, not implied.
  • The misleading feature in the stem is acknowledged and set aside with a reason.
  • Treatment specifies agent, strength, duration and follow-up interval.
  • Any time-critical window is stated with its number.
  • Contact or household management is addressed where relevant.
  • The post is submitted by Day 3 and before reading colleagues' posts.

Use this guide to plan and review your own work. Follow your institution's rules and read our academic-integrity policy.

Written by

Aaron Bishop

MA, Education

assignment interpretation and research-methods coaching across disciplines

Aaron leads the EssayCrackers editorial desk. He works on how assignment briefs are read — what a rubric is actually asking for, and where students most often answer a different question than the one set.

Reviewed by

Dr. Nathan Cole

PhD, Rhetoric & Composition

Argumentation and thesis development

Nathan teaches first-year composition and directs a university writing center. He reviews EssayCrackers guides for argumentative soundness and citation accuracy.

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