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NursingCase studyPsychopharmacology

NURS 6630 Dementia Decision Tree Assignment Guide

Three decisions on an elderly Iranian man with Alzheimer's — the marks are in why the other options were rejected, not in which drug you picked.

Updated

Editorial process

Last reviewed · August 9, 2026

01

Read the case as a clinician, not as a menu

The case is the assignment, so read it as a clinician rather than as a set of options. Mr. Akkad is elderly, Iranian, and brought to the clinic by his son — and every one of those three facts changes what a defensible decision looks like. Age narrows the safe starting dose and raises the weight you must give to bradycardia, falls and anticholinergic burden. The fact that a family member is the historian means your objective data on response arrives second-hand, so the reliability of that reporting is part of your clinical reasoning, not a detail. And the cultural context shapes what the family understands the diagnosis to be and what they expect a medication to do. Write the case back into your rationale explicitly, because a decision paragraph that would read identically for a 40-year-old with no family present is one that has not used the case at all.

The pharmacology you are being tested on is cholinesterase inhibition, and the three options are not interchangeable. Donepezil, rivastigmine and galantamine all raise synaptic acetylcholine, but they differ in half-life, in dosing frequency, in whether a transdermal route is available, and in how their gastrointestinal and cardiac effects present. That is the material difference the marker is looking for. Say why the agent you chose fits *this* patient — once-daily bedtime dosing where a son is supervising adherence is an argument; tolerability in an older man with unknown cardiac history is an argument; 'it is commonly used' is not. Name the pharmacokinetic property you are relying on, because the objective for this week asks you to analyse pharmacokinetic and pharmacodynamic processes and a rationale with no mechanism in it cannot satisfy that. Route matters too, since a transdermal option changes the conversation entirely when a family member is the one making sure a daily tablet is actually swallowed.

Decision Two is where most write-ups lose marks, because the case gives you a non-response and there are three genuinely different readings of it. A patient who shows no change at four weeks may be under-dosed, may be on the wrong agent, or may simply not have had enough time — cholinesterase inhibitors are conventionally judged over months rather than weeks. Your job is to say which of those you concluded and *why the other two were rejected*. Note also what the case tells you about side effects: an absence of adverse effects at the starting dose is positive evidence for titrating up rather than switching, and saying so shows you read the objective data rather than reaching for a change because the last decision did not work. The assignment asks you to explain any difference between what you expected and what happened, so state the expectation as a measurable one before you evaluate it.

Expected results have to be specific enough to be wrong. "The patient will improve" cannot be evaluated at the next decision point, which is precisely what the assignment then asks you to do. Commit to a domain, a magnitude and a timeframe — cognition on a repeatable measure, day-to-day function reported by the son, or a named behaviour such as returning to religious activity — and give the window over which you expect it. Then, when the case supplies the actual outcome, the comparison writes itself and the "why were they different" question has something to bite on. This is also what separates the three decision paragraphs from each other, since without stated expectations they collapse into three restatements of the same drug choice. A stated expectation also protects you at the next decision point, because a result you never predicted cannot be called a surprise and cannot be explained as one either.

The ethical and legal section is a required element and in dementia it is not generic. The specific problem is decisional capacity: the person taking the medication may not be the person consenting to it, and the son who brings his father to the clinic and reports on his response is not automatically his legal decision-maker. Address who holds capacity, how you would assess it rather than assume it, what surrogate arrangement applies, and how you would keep Mr. Akkad himself in the conversation to whatever extent he can be. Communication is named in the brief alongside the treatment plan, so say something concrete about how you would explain a slow, symptomatic, non-curative therapy to a family that may be hoping for reversal. Beneficence and autonomy are the right principles to reach for, but they earn nothing until they are attached to the specific decision you made about this patient.

Finally, the mechanics the brief states. Three academic resources minimum, and the course text does not count toward that three — so the Stahl chapters can support your reasoning but cannot be your evidence base. Each decision needs its rationale supported by references to the Learning Resources, which means citations distributed across the three decisions rather than banked in an introduction. And the structure is fixed by the brief itself: which decision, why, what you hoped to achieve, and how the result differed — four questions at Decision One and three at Decisions Two and Three. Answer them in that order under their own headings, because a marker working through a rubric built on those questions should not have to hunt for the answers. Give each decision its own citations as you draft rather than at the end, since a rationale written first and referenced afterwards tends to acquire sources that agree with it rather than sources that shaped it.

Decision point

The weak version

The version that scores

Decision 1 choice

Names a drug from the list

Names the agent and the property that suits this patient

Decision 1 rationale

It is first-line for Alzheimer's

Half-life, dosing schedule, tolerability in an older adult

Expected result

The patient will improve

A domain, a magnitude and a timeframe

Decision 2 reading

Switches agent because nothing happened

Distinguishes under-dosing, wrong agent and too-short trial

Use of the objective data

Ignores the absence of side effects

Treats tolerability as evidence for titration

Decision 3

Repeats decision 2's reasoning

Justifies maintenance against the alternative of escalation

Ethics

Cites beneficence and autonomy

Assesses capacity, names the surrogate, plans the conversation

Sources

Three Stahl chapters

Three academic sources beyond the course text

Likely learning objectives

Inferred from the brief — check these against your own rubric.

  • 01
    Select a cholinesterase inhibitor on properties that fit this patient.
  • 02
    Distinguish under-dosing from non-response and from an inadequate trial.
  • 03
    State expected results specifically enough to be evaluated later.
  • 04
    Address decisional capacity and surrogate involvement in dementia care.
Assignment instructionsQuoted verbatim

Read the full question

Review every instruction before using the planning guidance that follows.

Learning Objectives Students will: Assess client factors and history to develop personalized therapy plans for clients with dementia Analyze factors that influence pharmacokinetic and pharmacodynamic processes in clients requiring therapy for dementia Evaluate efficacy of treatment plans Analyze ethical and legal implications related to prescribing therapy for clients with dementia Learning Resources Note: To access this week’s required library resources, please click on the link to the Course Readings List, found in the Course Materials section of your Syllabus. Required Readings Note: All Stahl resources can be accessed through the Walden Library using this link. This link will take you to a log-in page for the Walden Library. Once you log into the library, the Stahl website will appear. Stahl, S. M. (2013). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). New York, NY: Cambridge University Press. To access the following chapter, click on the Essential Psychopharmacology, 4th ed tab on the Stahl Online website and select the appropriate chapter. Be sure to read all sections on the left navigation bar for each chapter. Chapter 13, “Dementia and Its Treatment” Stahl, S. M. (2014b). The prescriber’s guide (5th ed.). New York, NY: Cambridge University Press. To access information on the following medications, click on The Prescriber’s Guide, 5th ed tab on the Stahl Online website and select the appropriate medication. Review the following medications: For insomnia donepezil galantamine memantine rivastigmine Bui, Q. (2012). Antidepressants for agitation and psychosis in patients with dementia. American Family Physician, 85(1), 20–22. Retrieved from http://www.aafp.org/journals/afp.html Note: Retrieved from from the Walden Library databases. Meltzer, H. Y., Mills, R., Revell, S., Williams, H., Johnson, A., Bahr, D., & Friedman, J. H. (2010). Pimavanserin, a serotonin receptor inverse agonist for the treatment of Parkinson\’s disease psychosis. Neuropsychopharmacology, 35, 881–891. Retrieved from http://www.nature.com/npp/journal/v35/n4/pdf/npp2009176a.pdf Required Media Laureate Education. (2016h). Case study: An elderly Iranian man with Alzheimer’s disease [Interactive media file]. Baltimore, MD: Author. Note: This case study will serve as the foundation for this week’s Assignment. To prepare for this Assignment: Review this week’s Learning Resources. Consider how to assess and treat clients requiring therapy for dementia. The Assignment Examine Case Study: An Elderly Iranian Man With Alzheimer’s Disease. You will be asked to make three decisions concerning the medication to prescribe to this client. Be sure to consider factors that might impact the client’s pharmacokinetic and pharmacodynamic processes. At each decision point stop to complete the following: Decision #1 Which decision did you select? Why did you select this decision? Support your response with evidence and references to the Learning Resources. What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources. Explain any difference between what you expected to achieve with Decision #1 and the results of the decision. Why were they different? Decision #2 Why did you select this decision? Support your response with evidence and references to the Learning Resources. What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources. Explain any difference between what you expected to achieve with Decision #2 and the results of the decision. Why were they different? Decision #3 Why did you select this decision? Support your response with evidence and references to the Learning Resources. What were you hoping to achieve by making this decision? Support your response with evidence and references to the Learning Resources. Explain any difference between what you expected to achieve with Decision #3 and the results of the decision. Why were they different? Also include how ethical considerations might impact your treatment plan and communication with clients. Note: Support your rationale with a minimum of three academic resources. While you may use the course text to support your rationale, it will not count toward the resource requirement.
02

What each decision point must contain

  1. 01
    Decision #1 with the choice, the rationale, the expected result and the difference.
  2. 02
    Decision #2 with rationale, expected result and difference.
  3. 03
    Decision #3 with rationale, expected result and difference.
  4. 04
    A discussion of ethical considerations affecting the plan and the communication.
  5. 05
    A minimum of three academic sources, excluding the course text.
03

From the patient to the ethics

01

The patient before the pharmacology

Set out what age, family reporting and cultural context change about the decision.

02

Decision One: agent and dose

Choose a cholinesterase inhibitor and justify it on named properties.

03

Decision Two: reading the non-response

Separate under-dosing, wrong agent and insufficient time, and pick between them.

04

Decision Three: maintain or escalate

Justify continuation against the alternative of a further change.

05

Capacity, consent and the conversation

Address who decides, how capacity is assessed, and how the plan is explained.

04

Find the property that distinguishes the three agents

Recommended databases

  • PubMed Central
  • Cochrane Library
  • Walden Library
  • StatPearls

Search sequence

  1. 1.
    Find head-to-head or profile evidence on donepezil, rivastigmine and galantamine, since the rationale needs a property that distinguishes them rather than a general claim about cholinesterase inhibition.
  2. 2.
    Look for evidence on the safety profile in older adults specifically — bradycardia, falls, gastrointestinal effects — because age is the fact the case gives you and a generic safety statement wastes it.
  3. 3.
    Search for guidance on how long an adequate trial runs before non-response is declared, which is the pivot the whole of Decision Two turns on.
  4. 4.
    Find literature on capacity assessment and surrogate decision-making in dementia, so the ethics section rests on something other than the four principles.
05

Cholinesterase inhibitors, safety and capacity

These are authoritative starting points, not a ready-made bibliography. A qualified reviewer must confirm that each source fits the assignment and supports the claim beside which it is cited.

Nothing here is cleared for citation until you have read it.

  1. 01

    Donepezil for Alzheimer's disease: pharmacodynamic, pharmacokinetic, and clinical profiles

    CNS Drug Reviews · 2001

    Gives the pharmacokinetic and pharmacodynamic detail the rationale needs — half-life, dosing and selectivity — so the choice of agent can be argued from a property rather than from familiarity.

  2. 02

    Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study

    PLoS Medicine · 2009

    Evidence on a specific, serious adverse outcome in older adults, which is what turns a general statement about tolerability into a reason for monitoring this particular patient.

  3. 03

    Withdrawal or continuation of cholinesterase inhibitors or memantine or both, in people with dementia

    Cochrane Database of Systematic Reviews · 2021

    Directly supports Decision Three, where the question is whether to maintain the current regimen, by reviewing what the evidence says about continuing versus stopping.

  4. 04

    Capacity issues and decision-making in dementia

    Annals of Indian Academy of Neurology · 2016

    Grounds the ethics section in how capacity is actually assessed in dementia and how surrogate decision-making is structured, rather than in a restatement of autonomy and beneficence.

06

Before the decision tree is submitted

Common mistakes

  • Writing rationales that would read the same for any patient of any age.
  • Choosing an agent without naming the property that suits this case.
  • Ignoring that the son, not the patient, is the source of the objective data.
  • Reading the four-week non-response as failure without considering the dose.
  • Overlooking that no side effects at the starting dose argues for titration.
  • Giving expected results too vague to be evaluated at the next decision point.
  • Repeating Decision Two's reasoning at Decision Three.
  • Treating the ethics section as a paragraph on beneficence and autonomy in general.
  • Assuming the accompanying son is the legal decision-maker.
  • Counting Stahl toward the three-source requirement the brief excludes it from.
  • Banking all citations in an introduction rather than across the three decisions.

Submission checklist

  • Each decision states which option was selected and why.
  • At least one pharmacokinetic or pharmacodynamic property is named per choice.
  • The patient's age and family context appear in the reasoning.
  • Rejected options are addressed, not just the chosen one.
  • Expected results name a domain, a magnitude and a timeframe.
  • Each difference between expectation and outcome is explained.
  • Capacity assessment and surrogate arrangements are addressed.
  • The communication plan covers a non-curative, slow-acting therapy.
  • Three or more academic sources sit outside the course text.
  • Citations appear within each decision, not only in the introduction.

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